Study suggests possible link between Tylenol use in pregnant women and autism

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GRAND RAPIDS, Mich. --The headlines give pause: 'Pregnant women who persistently take OTC drugs for pain may increase kids' risk of autism.'

A new study suggests women who often take Tylenol while pregnant could increase their kids' risk for autism.

Researchers in Spain studied more than 2,000 mother-child pairs for roughly six years. Mothers were asked if they took Tylenol during pregnancy and, if so, how much. Researchers found that more than 40 percent of mothers reported persistent use of the drug. Their children scored lower on tests for hyperactivity, impulsivity, and other signs of autism.

But how much merit does the study actually hold? Dr. David Colombo, director of maternal fetal medicine at Spectrum Health says Tylenol has long been considered a safe medication for pregnant women to take for fevers and pain, and that shouldn't change -- at least for now.

"People put this out there, and there’s a lot of fear in pregnancy," said Colombo. "They’re always afraid, What am I doing to hurt my baby? There must be something trying to hurt my child." The Spanish study is nothing more than an association, Dr. Colombo added, and Tylenol isn't hurting your child one bit.


Colombo used a football analogy to explain: "Associations aren’t causations. I used to think when I used to wear my Cleveland Browns sweatshirt the Browns would win. Clearly, that didn’t happen; the Browns didn’t care if I wore that sweatshirt or not. But it could be I wore that sweatshirt when it was colder out, because it was thick, and maybe the Browns play better in colder weather for whatever reason. I was assuming it was my actions that were causing the win when in fact it was a coincidence, because they were both linked to a similar event."

Colombo says the association between autism and Tylenol could very well be the same. "Just because two things are increasing at the same rate doesn’t mean they’re causative," a reassurance for West Michigan mothers that taking Tylenol when needed is okay.

"Taking Tylenol doesn’t cause autism," said Colombo. "In fact we don’t even know what causes autism, and a lot of times we don’t know how to define autism. So it makes it very difficult."

Dr. Colombo says Tylenol should be the only pain killer pregnant women take, because aspirin and Ibuprofen can cause problems for babies. Dr. Colombo suggests only taking Tylenol when needed, do not take it in access amounts and consult your doctor before use.

Although this research could shed light on autism, experts admit more research needs to be done.

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  • Kevin Rahe

    Always more research needs to be done. Just like with the correlation between vaccines cultured using cells from an aborted baby and Autism. But is the research being done and who is doing it?

  • Ann Bauer Sc.D.

    Until the time that acetaminophen is proven safe, I would suggest that your viewers proceed with caution. Pregnant women should consult with their physicians before any use of acetaminophen. What Dr. Columbo failed to acknowledge is that this is the 5th human cohort study to investigate the use of prenatal acetaminophen and the 5th to suggest increased risk of autism/ADHD symptoms in offspring. Animal studies also support these finding. The links to these studies can be found here:

  • Annie McGill

    I’ve found that babies born where labor was induced have a very high incidence of autism and/or learning disabilities. Wonder if a study on these drugs used for inducing have been tested.

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